Inflammatory associated with lower colon cancer mortality

colon cancerDuring 2007, the United States were diagnosed in about 112,340 cases of colon cancer and 41,420 rectal cancer, which transforms the colorectal tumors in the third most common cancer in American men and women.

Regular and prolonged use of aspirin or other NSAIDs (ibuprofen or naproxen) reduce the risk of developing colorectal cancer, but so far not identified an increase in survival associated with the consumption of such drugs.

To investigate, Dr. Jason A. Zell, of the University of California at Irvine, analyzed data from 621 women study participants who had colorectal cancer.

Before diagnosis, 64 percent did not use NSAIDs regularly, 17 percent used between one and six days a week and 20 percent daily. 17 percent of women had used NSAIDs for less than five years and 18 percent, five years or more.

The team looked at women from the day of diagnosis until death or December 31, 2005, representing an average follow up of 3.4 years.

They found that regular consumption of NSAIDs before the diagnosis of colorectal cancer (one to three times per week, four to six times per week, or every day) was associated with a 42 percent lower risk of dying from cancer consumption is not regular.

Regular use of NSAIDs prior to diagnosis was associated with higher survival and regular use for five years or more was associated with increased overall survival and disease-specific.

If other studies confirm the results would have “significant impact in preventing cancer,” the authors in the journal Cancer.

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